Chemist Kathryn Harkup combines her scientific expertise and love of a good mystery in her first book, A Is for Arsenic: The Poisons of Agatha Christie. B is for belladonna, and C is for cyanide, as Harkup works her way through 14 mysteries and 14 discrete poisons, with meticulous and informed explanations of the science behind each toxin's effects (an appendix contains chemical structures). Each chapter also details famous real-life cases involving these deadly substances, including those that might have inspired--or been inspired by--Christie's work, and analyses of how accurately the Queen of Crime represented the science within her stories. Generally the renowned writer does very well: as Harkup explains, Christie worked as a volunteer nurse in World War I and showed such aptitude that she was encouraged to continue her education and training as a pharmacist. By the Second World War, her work as a dispenser left her ample time to pursue her other profession, writing bestselling stories and novels.
Harkup's writing style is accessible to the lay reader, although she does become technical when discussing poisons' actions on the body, with full detail at the cellular level. She keeps these explanations short, however, and general readers will be able to follow along. For Christie fans, the review of famous mysteries is great fun, and the few spoilers come with ample warning. A Is for Arsenic is both informative science and a spur to read or reread the most popular mysteries ever written. --Julia Jenkins, librarian and blogger at pagesofjulia